Confirmation


We use UPLC/MS/MS for drug confirmation. The superior performance of this technology leads to increased resolution in shorter run times can generate more information faster without sacrifices. UPLC takes advantage of technological
strides made in particle chemistry performance, system optimization,
detector design, and data processing and control.

It gives us a thumb print of the analyte in question which means that specificity is almost 100% which should be reassuring to providers that rely on drug test results for treatment decisions.

We currently test a large number of analytes and will only mention a few here. 

Amphetamines

Table 1-2. Amphetamines Confirmation Panel
Analyte Cuttoff Units Confirmation Method
Amphetamines 20 ng/mL LC/MS-MS
Methaphetamine 20 ng/mL LC/MS-MS
Methylenedioxymethamphetamine 20 ng/mL LC/MS-MS
Methylenedioxyethylamphetamine 20 ng/mL LC/MS-MS
Phencyclidine 20 ng/mL LC/MS-MS
Table 1-3. Opiates Confirmation Panel
Analyte Cuttoff Anticipated Date of Completion Confirmation Method
Codeine 20 ng/mL LC/MS-MS
Hydrocodone 20 ng/mL LC/MS-MS
Hydromorphone 20 ng/mL LC/MS-MS
Meperidine 20 ng/mL LC/MS-MS
Morphine 20 ng/mL LC/MS-MS
Tramadol 20 ng/mL LC/MS-MS
Oxycodone 20 ng/mL LC/MS-MS
Oxymorphone 20 ng/mL LC/MS-MS
Methadone 20 ng/mL LC/MS-MS
EDDP 20 ng/mL LC/MS-MS
6-AM Heroin Metabolite 20 ng/mL LC/MS-MS
Propoxyphene 20 ng/mL LC/MS-MS
Table 1-4. Benzodiazepines and Hypnotics Confirmation Panel
Analyte Cuttoff Units Confirmation Method
alpha-Hydroxyalprazolam 20 ng/mL LC/MS-MS
alpha-Hydroxymidazolam 20 ng/mL LC/MS-MS
7-AminoFlunitrazepam 20 ng/mL LC/MS-MS
7-Aminoclonazepam 20 ng/mL LC/MS-MS
7-Aminonitrazepam 20 ng/mL LC/MS-MS
Hydroxyflurazepam 20 ng/mL LC/MS-MS
Hydroxytiazolam 20 ng/mL LC/MS-MS
Chlorodiazepoxide 20 ng/mL LC/MS-MS
Nordiazepam 20 ng/mL LC/MS-MS
Diazepam 20 ng/mL LC/MS-MS
Oxazepam 20 ng/mL LC/MS-MS
Lorazepam 20 ng/mL LC/MS-MS
Temazepam 20 ng/mL LC/MS-MS
Carisoprodol 20 ng/mL LC/MS-MS
Zopiclone 20 ng/mL LC/MS-MS
Meprobamate 20 ng/mL LC/MS-MS
Zaleplon 20 ng/mL LC/MS-MS
Zolpidem 20 ng/mL LC/MS-MS
Table 1-4. Buprenorphine Confirmation Panel
Analyte Cuttoff Units Confirmation Method
Buprenorphine 20 ng/mL LC/MS-MS
Norbuprenorphine 20 ng/mL LC/MS-MS
Table 1-4. Cocaine Confirmation Panel
Analyte Cuttoff Units Confirmation Method
Cocaine 20 ng/mL LC/MS-MS
Cocaethylene 20 ng/mL LC/MS-MS
Benzoylecgonine 20 ng/mL LC/MS-MS
Codeine 20 ng/mL LC/MS-MS
Table 1-4. Marijuana Confirmation Panel
Analyte Cuttoff Units Confirmation Method
d9-THC 20 ng/mL LC/MS-MS
11-Nor-9-carboxy-d9-THC 20 ng/mL LC/MS-MS
Table 1-4. Barbiturates Confirmation Panel
Analyte Cuttoff Units Confirmation Method
Butalbital 20 ng/mL LC/MS-MS
Pentobarbital 20 ng/mL LC/MS-MS
Phenobarbital 20 ng/mL LC/MS-MS
Secobarbital 20 ng/mL LC/MS-MS


Please note that with many analytes customers can choose their cut-off levels, in some cases down to 1 ng/ml

 

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